Abstract
Introduction
Scleroderma or systemic sclerosis (SSc) is an autoimmune disease characterized by autoimmunologic processes, vascular damage, inflammation, and widespread activation of fibroblasts, in which the skin, esophagus, lung, heart, and kidneys are most likely to be impacted as the disease progresses. The pathophysiology and etiology of SSc are intricated and multifaceted. Numerous cell types, including fibroblasts, lymphocytic cells, endothelial cells, and epithelial cells, are typically involved.
Case Presentation
In this context, we present a case report of a 52-year-old Cambodian male patient who presented with the typical cutaneous presentation of scleroderma. Laboratory investigations revealed the presence of anti-Scl-70 antibodies, which are associated with severe systemic sclerosis. A potent topical steroid, antihypertensive medication, and anti-inflammatory agent were prescribed to control his symptoms. A three-month follow-up is mandatory to monitor the extent of organ involvement. This typical cutaneous presentation can serve as a crucial hallmark for physicians, allowing for an instant diagnosis through visual inspection.
Conclusion
Scleroderma is an uncommon autoimmune condition affecting more females than males. Although early signs of scleroderma are rare, they should not be overlooked. Systemic organ involvement should be strictly monitored so that management can be more effective. There has not yet been a curative treatment for this disease. However, the management of organ complications has made significant progress.